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Description
However, in Nrf 2/ mice, collagen secretion is increased due to activated pro-fibrosis signaling [135]
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Spironolactone's protective effects extend to preserving cardiac function, as evidenced by improved left ventricular ejection fraction and fractional shortening in treated rats [171]
Trials 22 , 116 (2021)
According to toxicity studies, it did not produce genotoxic, carcinogenic or teratogenic effects [16,[26], [27], [28]]
