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Description
[115] (2021) showed a significant decrease in IHLC after 6 weeks of a fructose-restricted diet in NAFLD, and Khodami et al
[DOI] [PubMed] [Google Scholar] 474
The first hit is the accumulation of fat in the liver, followed by the development of necrotic inflammation and fibrosis
Rodent models, however, permit controlled investigation of cellular and molecular mechanisms using transgenic manipulations that mimic human disease
(PubMed) Diez-Ricote L, San-Cristobal R, Concejo MJ, et al
doi: 10.1021/acs.chemrestox.0c00479
