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10.1016/j.scr.2013.05.003 [DOI] [PubMed] [Google Scholar] Sato H., Imamura R., Suga H., Matsumoto K., Sakai K

Preclinical interaction studies typically cost $15,000$40,000 per compound pair, depending on the complexity of pharmacokinetic assays, CSF penetration analysis, and behavioral monitoring required