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Using highly multiplexed antibody staining with imaging mass cytometry, we identified the emergence of stress-associated microglia (SAM) using a spatial proteomics method in the brains of 2HIT mice, which highly express TGF, APOE, MHC-class II, IL-6, and TREM2 proteins

They also indicated the possibility of dual role of KIM-1 beyond tubular injury biomarker it is involved in regeneration process and as such may be a potential marker of renal repair

7:1034-1043 (2022) Acknowledgements This study was financially supported by the Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries (IPET) (RS-2025-02218354) and by the R&D Program of MOTIE/KEIT (RS-2025-02307907)

However, the NAD + functions in innate immune cells are complex and context-dependent

Interactions of cytokines, S-adenosylmethionine, and S-adenosylhomocysteine in alcohol-induced liver disease and immune suppression