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The abundance of GSH is unusually high, the cytosol concentration is ca 111 mM, mitochondria contain 610 mM, and nuclei 315 mM of GSH

Mice that have had the glutamate-cysteine ligase (GCL) gene knocked out do not develop beyond the embryo stage and die before birth

However, these studies were not able to elucidate how microbiome alterations correlate to the antiseizure effect of the KD

Conversely, copper can also induce cytotoxicity through ROS accumulation and high mitochondrial-dependent energy metabolism, in a process called cuproptosis (374, 375)

Choice C: CD40 is a costimulatory protein found on antigen-presenting cells like B cells and macrophages

All studies were also cross- sectional in nature, which limits conclusions that can be drawn
