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Separate preclinical studies have examined BPC-157 in rat tendon explants and fibroblasts and thymosin beta-4 in rat wound and keratinocyte-migration models

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LL-37 is generated from a much larger precursor protein known as hCAP-18 (human cationic antimicrobial protein, 18 kilodaltons)

109 used a brush functionalization technique to create a gradient of TGF-3, decreasing in concentration from the articulating surface to the subchondral region, and likewise created a reverse gradient of BMP-2

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