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This article clearly distinguishes between FDA-approved uses (none) and investigational findings

Neurology 71(22):17701775 Vincent AM, Mobley BC, Hiller A, Feldman EL (2004) Igf-i prevents glutamate-induced motor neuron programmed cell death

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In addition, PDGFR/ amplification, overexpression, and constitutive activation contribute to anti-IGF-IR mAb resistance [179, 180]

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