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Published research on these studies documented outcomes from approximately 900 adult participants, predominantly individuals classified as clinically obese, though one trial included healthy non-obese volunteers

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For individuals with BMI above 30 or BMI above 27 with comorbidities, FDA-approved GLP-1 receptor agonists (semaglutide, tirzepatide) have far stronger evidence and produce dramatically greater weight loss

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Some of these, such as genetics, are out of the persons control

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