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Nrf2 knockdown prevents NFT-dependent increase in cellular glutathione levels To examine the correlation between Nrf2 activation and the increase in glutathione levels after NFT treatment, Nrf2 protein levels were experimentally lowered by siRNA-mediated knockdown, which was confirmed by Western blotting (Fig
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In humans, AA and linoleic acid are the most abundant PUFA that serve as the preferred oxidation site for LOXs using molecular oxygen to form hydroperoxyl radicals at different carbon position of acyl chains

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[DOI] [PubMed] [Google Scholar] 156.Punganuru S.R., Mostofa A.G.M., Madala H.R., Basak D., Srivenugopal K.S