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In a 4-week open-label study of 5 PD patients and 3 healthy controls, high-dose oral NAC (6000 mg/day) markedly enhanced peripheral antioxidant capacity but failed to elevate brain GSH levels

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Here we show that depletion of intracellular GSH does not alter tumour growth and extracellular GSH is highly abundant in the tumour microenvironment, highlighting the potential importance of GSH outside tumours

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References: Davies MJ, Bajaj HS, Broholm C, et al
