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As is known, microglia and astrocytes play an important role in regulating the levels of inflammatory cytokines in the brain [38]

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Cooper BM, Iegre J, ODonovan DH, Halvarsson M, Spring DR (2021) Peptides as a platform for targeted therapeutics for cancer: peptidedrug conjugates (PDCs)

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The trial also showed that the combination produced dose-dependent, sustained weight loss without concerning additional adverse effects the side effect profile was broadly consistent with what would be expected from each individual agent