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Although several biological targets for CTX have been proposed, direct binding has not been reported

Contrary to this phenomenon, in colorectal cancer cell line models, the HMOX1 gene has SMARCA4 suppression that reduces NRF2 binding to transcriptional regulatory regions and reduces gene expression 29

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Here we show that Trr1 is required during normal cell growth, whereas there is no apparent requirement for Glr1

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