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Additionally, SFN combined with 5-aza-2-deoxycytidine and trichostatin A significantly reduced the CpG methylation levels in the NRF2 promoter region and inhibited the protein expression of DNA methyltransferase 1 (DNMT1), thereby promoting NRF2 expression, which may play a preventive role in colon cancer [151]

doi: 10.1016/j.autrev.2014.01.007

doi: 10.1016/j.tcb.2022.02.009 50 ZhuJBerisaMSchworerSQinWCrossJRThompsonCB

GSH (Reduced glutathione) is the active form of glutathione that helps your cells stay healthy by fighting off harmful substances called free radicals

380 Deficiency of TFR1 in skeletal muscle results in abnormal blood iron and lipid metabolism, impairing muscle function

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