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The short half-life generally results from rapid renal clearance, enzymatic digestion by proteases, or both [1]
It causes fevers, chills, and low blood pressure

This specificity sets it apart from older-generation secretagogues

Time of peptide intake depending on digestive system ailments (stomach ulcers, leaky gut syndrome, heartburn, and hyperacidity): Taking peptides on an empty stomach causes a faster increase in their concentration in the blood

3.5 Meta-analysis The included studies showed substantial heterogeneity (I 2 = 99.6%, p 0.05), supporting the conclusion of comparable efficacy and the lack of a clear doseresponse relationship
