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(Outlines contraindications for niacin therapy, including active peptic ulcer disease, active liver disease with elevated enzymes, hypersensitivity to niacin, and arterial bleeding, as well as monitoring recommendations for blood pressure, glucose, uric acid, etc., due to niacins systemic effects)

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There was no significant difference in richness, however there was a trend towards a decrease in richness in obese versus lean animals over time ( p = 0.20, p = 0.024 and p = 0.320) (Fig

Corban MT, Godo S, Burczak DR, et al