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It will be shown that these various and non excusive susceptibilities may lead to a set of positive feedback loops that can become self-sustained, even in the absence of a persistent pathogen, but more efficiently in case of pathogen persistence

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Known for its strong antibacterial, anti-inflammatory, anxiolytic, sedative, antidepressant, analgesic, anticonvulsive and neuroprotective potenitial, it is particularly effective in reducing pain and inflammation, possibly through COX enzyme inhibition (Koulivand et al., 2013)

However, while they offer unique advantages, there are several limitations that researchers must consider: Differences in Physiology Although zebrafish share around 70% of human genes, their physiology differs significantly in areas such as immune system composition, metabolism, and hormonal regulation

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doi: 10.1016/j.heliyon.2022.e10819 23 OSullivanC.SchubartA.MirA