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The authors established FOXO4-DRI as a first-in-class senolytic peptide tool for cellular senescence research, with mechanistic selectivity grounded in the elevated FOXO4-p53 interaction in senescent versus non-senescent cells

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To confirm this, we performed immunohistochemistry on sectioned TA muscles and observed that CD3 + T cells are detected more abundantly at day 5 compared to day 0 in the TAs of young, old and geriatric mice (Fig

[108] In addition, certain drugs may interfere with laboratory tests for the vitamin, such as amoxicillin, erythromycin, methotrexate and pyrimethamine

This review discusses the development of novel antiobesity drugs based on current understanding of energy homeostasis Keywords: Obesity, Pharmacotherapy, Drug targets

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