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The stable NRF2 accumulate in the nucleus, where it binds to antioxidant response element (ARE) in the DNA and induces the expression of target genes [78]

Adv Microb Physiol 57, 43117

doi: 10.2147/DDDT.S493049 163 MehlenbacherMRElsiesyRLakhaRVillonesRLEOrmanMVizcarraCLet al

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Antidepressant discontinuation syndrome occurs when people suddenly stop taking or drastically reduce their dosage of antidepressant medication after taking it with some consistency for at least one month

That increased energy and mental clarity often happens surprisingly quickly