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As is well known, Ras-related protein Rab-27AA (Rab27), Ras-related protein Rab-17 (Rab17), and cell division control protein 42 (Cdc42) belonging to Rho GTPase family are closely involved in the regulation of intracellular vesicle trafficking due to their roles in endocytosis [165]

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The carboxyl-terminal fragment of hGH corresponding to amino acids 177191 (AOD9604) was shown to act as a lipid mobilizing domain with inhibitory action on acetyl-CoA carboxylase (ACC) activity in hepatocytes and adipocytes