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The autophagic degradation of ferritin, NCOA4-mediated ferritinophagy, disrupts the ratio of ferritin-stored iron to free redox-active iron in favor of the latter [103]

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Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is the gold standard for quantifying dihexa in plasma, with a lower limit of quantification typically around 15 ng/mL depending on sample preparation and ionization efficiency

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Outgrowth times are shown in Supplementary Table 5
