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However, exclusive use of folic acid in treating vitamin B12 deficient megaloblastic anemia could result in progressive and irreversible neurologic damage

In this context, PLGA nanocarriers have emerged as an effective platform for delivering pharmacological agents and natural compounds including essential oils 100 , plant extracts 101 , and bioactive molecules 102,103

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S-glutathionylation in human platelets by a thiol-disulfide exchange-independent mechanism

PCR analyses confirmed that the neuroprotective activity was mediated through modulation of the Wnt/ -catenin and PI3K/Akt/GSK-3 signaling pathways (91)