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Enhanced sinusoidal glutathione efflux during endotoxin-induced oxident stress in vivo

High levels of caffeine can also stress the adrenal glands, indirectly affecting the body's ability to maintain balanced glutathione levels

This work was supported by the Japan Society for the Promotion of Science (JSPS) Grant-in-Aid for Young Scientists (B) Grant Number JP15K19036 (SH), JSPS Grant-in-Aid for Young Scientists Grant Number JP19K16271 (SH), Japan Science and Technology Agency (JST) ACT-X Grant Number JPMJAX201A (SH), RIKEN FY2018 Incentive Research Projects (SH), and Naito Grant for female scientists after maternity leave (SH)

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Mexican populations in our study have a highly enriched MTHFD1 1958AA frequency (~35 %) due to their Amerindian ancestry, as shown in the Nahuas, Totonacas and Zapotecos in our study presenting a MTHFD1 1958AA frequency of ~60 %