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There is also concern that the addition of glutamate may increase the osmotic pressure of the medium
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Front Plant Sci 11:485932
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doi: 10.1097/00001756-200102120-00032 202 DavidsonSGoldenJPCopitsBARayPRVogtSKValtchevaMVet al
however these ligands have some handicaps, such as their low binding capacity, cost-efficacy issues, some problems in scale-up and purification process
