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Its dual function as both a signalling molecule and a copper transporter, combined with its ability to modulate thousands of genes, gives it a breadth of activity that most synthetic peptides lack

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doi: 10.14348/molcells.2016.0164

doi: 10.1152/ajpcell.00283.2008

Research indicates that FOXO4-DRI can selectively remove senescent cells in chondrocytes, which are the cells found in cartilage
