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Oda SS, et al

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Additionally, it negatively affects the activity of energy metabolism-related neurons in the hypothalamic arcuate nucleus (e.g., increases appetite and energy intake by elevating spiny mouse state-related protein: agouti related protein (AgRP) neurons and decreasing levels of allantoinogen proopiomelanocortin (POMC) neurons)

By mimicking the enzymatic activities of superoxide dismutase and catalase, nanoceria effectively reduce oxidative stressa key factor in AMD pathogenesis [153]

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This inhibition prevents fatty acid breakdown while synthesis occurs