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doi:10.1016/j.phymed.2020.153395

it modulates immune responses while maintaining cellular homeostasis by coordinating the mitochondrial-ER interaction network, providing important insights for developing novel metabolic immunomodulators from traditional medicines (93)

9 However, NAPQI is rapidly detoxified by interaction with glutathione to form cysteine and mercapturic acid conjugates

It can also reflect iron deficiency, blood sugar instability, hormone shifts, nervous system dysregulation, or chronic stress