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This pathway is active during brain development and plays a role in neural repair after injury
& Koutsilieris, M
Efforts to discover new PPAR agonists without adverse effects led to the development of dual agonists (glitazars) that activate both PPAR and PPAR, thus combining successfully (4) the lipid-lowering effects of PPAR with the insulin-sensitizing effects of PPAR

Such improvements may improve patient convenience, treatment adherence and reduce costs for the healthcare system

Biomaterials 284, 121491

2022;7:e158308