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Rare but serious side effects include pancreatitis, diabetic retinopathy, thyroid tumors, and kidney damage

To learn more about how NAD+ production works, visit our educational guide: Can NAD+ Reverse Aging? Exploring the Science and the Hype

The side effect profile is similar to those of the component medications and includes conjunctival hyperemia (63%), instillation site pain (23%), conjunctival hemorrhage (13%) and verticillata (17.6%)

Rhein treatment could significantly reduce the level of uric acid, which plays a detrimental role in the integrity of the intestinal barrier

It encourages healthy weight management and cardiovascular health with the ability to decrease fat mass, improve athletic performance and reduce fatigue

If you're pregnant or breastfeeding, consult your doctor before getting vitamin B12 shots