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913 This finding has led several liver societies to recommend separate sex-based upper limits of normal

A review, Exp

Moreover, the detection of a sulfurized afatinib fragment ion resulting from fragmentation of the CS bond between the thiol and the cysteine -carbon further confirmed covalent thiol addition to afatinib

As will be discussed, one mechanism which may connect thiol-metal binding to oxidative stress-mediated toxicity is specific of Hg, the cysteinyl-glycine bound form of which is able to deplete glutathione reservoirs by a catalytic process [34]

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GSH protects cells from oxidative stress-induced apoptosis by scavenging H 2 O 2 , and exogenous GSH supplementation enhances cell viability under oxidative conditions 34