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10.1093/gerona/60.10.1315 J

Extracellular Glutathione Peroxidase GPx3 and Its Role in Cancer

It is indicated by the data of this study, that auranofin interacts with thioredoxin-glutathione reductase through a selenocysteine mediated transfer of gold from auranofin to Cys sites and gold provides the inhibitory activity, essentially making auranofin the pro-drug for gold delivery ( Leishmania infantum , offers insight into auranofin interference of the redox system by inhibiting trypanothione reductase, an enzyme that replaces many of the thioredoxin/TrxR and glutathione/glutathione reductase functions

First, convert milligrams (mg) to micrograms (mcg): 10mg = 10,000mcg

FGF, Fibroblast growth factor

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