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Some pharmaceutical medications may increase the need for ALC, including AZT, certain antibiotics, isotretinoin, and some anti-seizure medications (carbamazepine, phenobarbital, phenytoin, and valproic acid)

Glutathione works at the cellular level, reducing the oxidative stress that drives melanin overproduction, whilst Niacinamide inhibits melanosome transfer to prevent pigment distribution

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