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The existing research is almost entirely in rodents, with inconsistent methods that dont meet regulatory standards
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A neurobiological model of insomnia

For background on the broader angiotensin IV / AT4 system the work was built on, see Wright and Harding 1995 (PMID 7768321) and Wright et al

share the binding affinity) but have the additional advantage of increased protease resistance that motivates also our work

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