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4,5 Dietary insufficiency, pernicious anemia (i.e., an autoimmune process that reduces available intrinsic factor and subsequent absorption of vitamin B 12 1,2,6,7 ), and long-term use of metformin or acid-suppressing medications have been implicated in B 12 deficiency

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Initial investigations typically include a full blood count (including MCV), serum B12 and folate levels

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peptide clinics and compounding pharmacies make AOD9604 available, but its typically labeled for research purposes only to comply with DSHEA (Dietary Supplement Health and Education Act) regulations (FDA compounding context)

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if you ingest them, your stomach acid typically destroys them before they can enter your bloodstream to do their work

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The study of pernicious anemia patients with relapse of anemia (Figure 10) (53) has shown that the depletion of serum vitamin B-12 after folic acid administration is accompanied by a proportional increase in reticulocyte counts, suggesting that serum vitamin B-12 is diverted into the hematopoietic system to provide the necessary vitamin B-12 coenzyme for methionine production

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