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Nearly 40% of people with PCOS have trouble getting pregnant naturally, but early research shows that GLP-1 agonists may increase natural pregnancy rates, either on their own or when combined with metformin, more effectively than metformin alone

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There is no human trial of this exact combination, so the evidence here is built from studies on the individual components, most of it preclinical

As a result, research teams can maintain efficient workflows while improving consistency and control across studies

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