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Further, rather than being associated with the categorical diagnosis of MDD, TL may be associated with specific symptoms frequently associated with MDD such as anxiety 35,36,37 , and this comorbid symptom has been inadequately studied in relation to TL

The use of antiepileptics in CVS prophylaxis has been studied in a few clinical trials (155, 157160) (Table 7)

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The denaturants then must be completely removed to allow proper refolding of the protein

The carnosine showed a weak trend (F = 2.464, p = 0.094), with the highest concentration in HC (3.88 mM), intermediate in long COVID (3.03 mM) and lowest in CFS/ME (2.88 mM)