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Research indicated that GA exhibited preventive and therapeutic effects on ASCVD, including diabetes, obesity, hyperlipidemia, hypertension, atherosclerosis, cerebral ischemia, and myocardial infarction

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Corts-Albornoz MC, Garca-Guqueta DP, Velez-van-Meerbeke A, Talero-Gutirrez C

Here the original carbon skeleton R has been altered so that the new backbone R 1 carries additional functional groups (e.g., carbonyls, alcohols, or extra nitrate groups)