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GLP-1 therapies improve endothelial signaling, which enhances nitric oxide production

however, current evidence remains insufficient to draw firm conclusions, especially concerning mechanistic impacts on disease activity, optimal timing of GLP-1RA initiation, safety considerations in the IBD population and potential pharmacological interactions

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This compounds the effects of Metabolic Adaptation and contributes to The GLP-1 Plateau

Picrosirius red and Oil Red O staining
