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Neurological manifestations are particularly concerning and may include peripheral neuropathy with paresthesias (tingling and numbness in hands and feet), ataxia, impaired proprioception and vibratory sense, cognitive impairment, memory loss, and in severe cases, subacute combined degeneration of the spinal cord

For instance, Too much B6 can be toxic to the nerves

Designing nanomedicine for immuno-oncology

"Two-Year Trends of Taxane-Induced Neuropathy in Women Enrolled in a Randomized Trial of Ace-tyl-L-Carnitine (SWOG S0715)." natl cancer inst 1(110): 669-676

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is supported by the Hallas Mller Investigator award from the Novo Nordisk Foundation