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Intestinal gluconeogenesis prevents obesity-linked liver steatosis and non-alcoholic fatty liver disease
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Since, the juvenile worms of Isoparorchis hypselobagri penetrate the intestine, liver and swim bladder before transforming into an adult stage, we hypothesise that the migrating juvenile worms cause tissue damage that could result in the down-regulation of antioxidant enzymes

Other clinical criteria of lipedema comprise spontaneous or minimal trauma induced bruising, pain, and worsening during the day [5,14]

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