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Nature 571:515520 BonDurant LD, Ameka M, Naber MC, Markan KR, Idiga SO, Acevedo MR, Walsh SA, Ornitz DM, Potthoff MJ (2017) FGF21 regulates metabolism through adipose-dependent and -independent mechanisms

Moreover, an in vitro study demonstrated that human CRP directly contributes to adaptive immunity, with its native form specifically binding to human Jurkat T cells and to mouse naive CD4 + T cells, modulating their Th1 and Th2 responses and thus alleviating experimental autoimmune encephalomyelitis [116]