l carnitine an L-Carnitine | Linus Pauling Institute Energy Gel with L-Carnitine Box
Description
Interactions with medications L-carnitine may interact with some medications, such as anticoagulants , antihypertensives or thyroid medications
In recent years there has been considerable interest in the therapeutic potential of L-carnitine and its acetylated derivative acetyl-L-carnitine (ALCAR) for neuroprotection in a number of disorders including hypoxia-ischemia, traumatic brain injury, Alzheimers disease and in conditions leading to central or peripheral nervous system injury
The long chain fatty acids first bind to CoA to form the fatty acyl CoA that in turn binds with l-carnitine, and the resulting acylcarnitine is shuttled through the inner membrane and into the mitochondria (Figure 2)
When Na + is substituted for another monovalent cation caesium (Cs + ), no current is observed upon the addition of carnitine, demonstrating the Na + dependence of carnitine transport
Srinivas SR, Prasad PD, Umapathy NS, Ganapathy V, Shekhawat PS
PMID 1321584
