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doi: 10.3389/fphar.2022.856914

Introduction Metabolic dysfunction-associated fatty liver disease (MAFLD), formerly named as non-alcoholic fatty liver disease (NAFLD), is characterized as excessive lipid accumulation within hepatocytes with overweight/obesity, presence of type 2 diabetes mellitus, or evidence of metabolic dysregulation (Vernon et al., 2011)

Compared to the 25% of subjects with the lowest plasma TMAO levels at baseline, the 25% with the most TMAO in their blood were 2-3 times more likely to suffer a nonfatal heart attack, a stroke, or a fatal CVD event

Comparison of NPSfinder Findings With EDND or EWA Databases The large number of unique molecules that were uniquely identified by NPSfinder can be explained with the innovative methodology that NPSfinder used for the early identification of all NPS, including CEs ( is able to automatically scan the web for new/novel/emerging NPS on a 24/7 basis

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[DOI] [PubMed] [Google Scholar] Kranzler HR, Covault J, Pierucci-Lagha A, et al