nadph dependent glutathione reductase Pathways Harnessing the Mechanism of Glutathione

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More recent findings suggest that NAC corrects the alterations in glutamate homeostasis associated with drug addiction by inducing GLT1, a glial transporter that clears extracellular glutamate and inhibits the activation of extrasynaptic receptors that are involved in the induction and expression of maladaptive synaptic plasticity, such as mGlu5 receptors [117]

doi: 10.1016/j.envpol.2017.11.041

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Hardie LJ, Briggs JA, Davidson LA, Allan JM, King RF, Williams GI, Wild CP