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The major pathological features of COPD are obstructive bronchiolitis, emphysema, and mucus hypersecretion [59]

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Theoretical and reported concerns Off-target cell death: no compound is perfectly selective, so healthy cells with temporarily high FOXO4 could be affected in theory

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Gene length corrected trimmed mean of m-values (GeTMM) processing of RNA-seq data performs similarly in intersample analyses while improving intrasample comparisons