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The surgical implantation of the cannula involved anesthetizing the mice with isoflurane
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Some research studies that suggest if you take a probiotic while taking antibiotics, you're less most likely to obtain diarrhea caused by the antibiotic

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In fact, the effect of circulating leptin on mature bone cells is mainly exerted through the CNS, instead of local direct actions in vivo (136, 145, 482)

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