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On the other hand, it is not advised to use these drugs for a long-term since the protein expressions of CYP isozymes involved in steroidogenesis as well as the numbers of spermatocytes in testes were decreased.

Perfect For: Dogs with diagnosed heart disease (heart murmurs, DCM, valve disease), breeds predisposed to heart problems (Cavaliers, Dobermans, Boxers, Great Danes, Cocker Spaniels, Golden Retrievers), senior dogs (7+ years), dogs on grain-free diets (at risk for taurine deficiency), overweight or diabetic dogs, dogs with high blood pressure or cholesterol, dogs with low energy or exercise intolerance, dogs with coughing or breathing changes, or any dog whose owner wants proactive heart and metabolic protection