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NCCIH-funded hepatitis C trial: A high-quality study of 154 people with hepatitis C randomized to placebo, 420 mg, or 700 mg of silymarin (Legalon) daily found that silymarin in combination with interferon was no different from placebo (Fried, JAMA, 2012) [30]

However, increased antioxidants are generally beneficial during pregnancy

Additionally, thyroid hormones were reported to affect spermatogenesis, Leydig, and Sertoli cells

However, they are also interconnected, and changes in one can affect the other

[PubMed] [Google Scholar] 26.Mitsuyama H, May JM
