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One could expect an enhancement of the type 1 IFN response seen in the R47H to be a beneficial mutation if it means a more aggressive containment of the virus, but this could also be interpreted as an overactive immune response that leads to enhanced collateral damage

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Vaccines 9:679

Part of it is confusing correlation with causation, seeing a molecule in tumor cells and assuming it drives the disease rather than reflecting the body's response

Tankyrase inhibition blocks Wnt/-Catenin pathway and reverts resistance to PI3K and AKT inhibitors in the treatment of colorectal cancer

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