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Funding The present study was funded by a PhD grant from the Research FoundationFlanders (FWO grant 1SH5N24N)
Animal work indicates tissue healing and blood-vessel impacts, but animals metabolize drugs differently and dosing frequently exceeds human use
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but, in high-risk patients, they should be viewed as an addition to medication therapy rather than its replacement
Pain that is worse when lying flat or that lasts for hours requires urgent evaluation
