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Immunofluorescence analysis confirmed the elevated ROS levels in cells with an inhibited NF-B pathway (Fig

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Kim KA, Kim YS, Park SH, Chung WJ, Choi DH, Jang ES, et al

Apelin-13, a peptide hormone, is reported to increase the expression of SFXN1 and nuclear receptor coactivator 4 (NCOA4), inducing ferroptosis via ferritinophagy and the shuttling of Fe 2+ into mitochondria [98, 99] (Fig

Bronchial and bronchiolar epithelium was either negative or weak (65/69), but by immunohistochemistry the alveolar epithelium was always positive in stage IV COPD